Acute intermittent porphyria AIP is a rare autosomal dominant metabolic disorder affecting the production of heme resulting from a deficiency of the porphobilinogen deaminase. It is the most common of the acute porphyrias. The clinical presentation of AIP is highly variable and non-specific. The patients are typically asymptomatic, with most gene carriers having no family history because the condition had remained latent for several generations. AIP is one of the four porphyrias that presents as an acute attack. Patients usually experience symptoms in attacks that last from several hours to a few days.
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The Biological Basis of Schizophrenia pp Cite as. I want to consider schizophrenia as an inborn error of metabolism by comparing it with a disease in which the inborn error is already known. The disease chosen as a model for comparison is acute intermittent porphyria. The clinical material which has formed the basis for the comparison consists of two pedigrees, one of which has suffered from schizophrenia and the other from acute intermittent porphyria.
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Wetterberg, L. A neuropsychiatric and genetical investigation of acute intermittent porphyria. Report on an international survey of safe and unsafe drugs in acute intermittent porphyria. Doss and P. Nawrocki, eds. Pharmacological and biochemical properties of kryptopyrrole and its oxidation products possibly related to acute intermittent porphyria. Wetterberg There are no affiliations available. Personalised recommendations. Cite chapter How to cite?
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Pathogenesis and treatment of acute intermittent porphyria.
Akut intermittent porfyri (AIP)